Surgery

Surgery

Surgical Procedures for Breast Cancer

Currently, almost all women who receive a diagnosis of breast cancer undergo surgery as well as radiation therapy. Surgery is the first step in accurately determining the stage of your breast cancer and deciding on the best treatment option. If you have breast cancer, your doctor will likely perform one of the following procedures to remove your tumor:

Mastectomy

Partial mastectomy

    – Lumpectomy

    – Excision

    – Quadrantectomy

The type of surgical procedure will depend on the stage of the breast cancer and size of the tumor. Your surgeon might use terms such as breast-saving, breast-preserving, or breast-conserving surgery to describe the procedure. This means the tumor and cancerous tissue will be removed, while as much of your breast as possible will be preserved.

It's important to discuss your procedure with your surgeon so that you'll know how much breast tissue will be removed and what to expect after surgery. Although many surgeons do not discuss plastic surgery options, breast reconstruction can be part of your total breast cancer care. Before you have surgery, talk with your doctor about whether you're a candidate for breast reconstruction. He or she may want to include a plastic surgeon as part of your surgical team.

Lumpectomy

Lumpectomy involves removing the tumor (or lump) and tissue surrounding the tumor. The tissue is then carefully examined to be sure no cancer cells remain in the normal tissue, or margins, that surround the tumor.

If cancer cells are found in the surrounding tissue, your surgeon will perform another surgery, or excision, to remove the remaining cancerous tissue and check again for cancer. Once the tissue is considered clear of cancer cells, radiation therapy is likely to be used as follow-up treatment to prevent the cancer from coming back.

The combination of lumpectomy and radiation therapy is known as breast conservation therapy. Studies have shown that overall survival is similar for patients treated with lumpectomy plus radiation compared with those treated with surgery to remove the entire breast (modified radical mastectomy). Still, many surgeons and patients choose mastectomy over combination lumpectomy with radiation therapy.

Conclusion

Because each patient is different, breast surgery and treatment should be tailored to the individual. To decide the best course of treatment, your surgeon will evaluate your medical and family history, risk factors, current medications, and imaging results (including mammograms, ultrasounds, magnetic resonance images [MRI]), as well as the stage of the cancer and size of the tumor. Depending on your case, your doctor also may discuss breast reconstruction options. Good communication between you and your doctor will help you know what to expect after your surgery and throughout your treatment.

Learn more about Femara patient programs Learn more about Femara patient programs

*The Femara Cares Program™ Prescription Discount Card allows you to pay only $10 for your Femara prescriptions, if you are eligible. Novartis Pharmaceuticals Corporation will pay the rest, up to a maximum of $800 in any 12-month period, toward your Femara prescriptions. This card is subject to change or termination at any time.

Not all patients will receive a total of $800 per year off their prescriptions. Total value of card determined by applicable patient co-pay or out-of-pocket cost.

The Femara Cares Program™ Prescription Discount Card is not valid for prescriptions for which payment may be made in whole or in part under federal or state healthcare programs, including but not limited to, Medicare or Medicaid, or for residents in MA. Limitations apply.

 

Indication
Femara® (letrozole tablets) is approved for the adjuvant (following surgery) treatment of postmenopausal women with hormone receptor-positive early stage breast cancer. The benefits of Femara in clinical trials are based on 24 months of treatment. Further follow-up will be needed to determine long-term results, safety and efficacy.

Femara is also approved for the extended adjuvant treatment of early stage breast cancer in postmenopausal women who are within three months of completion of five years of tamoxifen therapy. The benefits of Femara in clinical trials are based on 24 months of treatment. Further follow-up will be needed to determine long-term results, including side effects.

In addition, Femara is approved for the treatment of postmenopausal women with estrogen receptor-positive or estrogen receptor-unknown breast cancer that has spread to another part of the body (metastatic cancer). Femara is also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.

Important Safety Information

You should not take Femara if you are premenopausal. Your doctor should discuss the need for adequate birth control if you have the potential to become pregnant, if you are not sure of your postmenopausal status, or if you recently became postmenopausal. Femara is only indicated in postmenopausal women. Talk to your doctor if you're allergic to Femara or any of its ingredients. You should not take Femara if you are pregnant as it may cause harm to an unborn child. Some women reported fatigue and dizziness with Femara. Until you know how it affects you, use caution before driving or operating machinery. Some patients taking Femara had an increase in cholesterol. Additional follow-up is needed to determine the risk of bone fracture associated with long-term use of Femara.

In the adjuvant setting, commonly reported side effects are generally mild to moderate. The most common side effects seen with Femara include hot flashes, joint pain, night sweats, weight gain, nausea, tiredness, other heart-related events, and bone fractures. Other less commonly reported side effects include vaginal bleeding, blood clots, other cancers, osteoporosis, stroke, heart attack, and endometrial cancer.

In the extended adjuvant setting, commonly reported side effects are generally mild to moderate. Commonly reported side effects for Femara include hot flashes, fatigue, joint pain, headache, increase in sweating, swelling due to fluid retention, increase in cholesterol, dizziness, constipation, nausea, heart-related problems, muscle pain, osteoporosis, arthritis, and bone fracture.

In the metastatic cancer setting, commonly reported side effects are generally mild to moderate and may include bone pain, hot flashes, back pain, nausea, joint pain, shortness of breath, tiredness, coughing, constipation, limb pain, chest pain, and headache.

Femara is a once-daily convenient prescription tablet.

For additional safety information, please see the prescribing information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call
1-800-FDA-1088.